Messi was a mainstay of Guardiola's Barca side that won 14 major titles and has been linked with a switch to City
Cristiano Ronaldo, Gareth Bale and Karim Benzema took Real Betis apart to give Real Madrid a resounding 5-0 win on Saturday that put them level on 50 points with Barcelona and Atletico Madrid at the top of La Liga.
Cristiano Ronaldo grabbed a hat-trick and Gareth Bale became the fifth British player to score for Real Madrid at the Bernabeu in La Liga when he struck twice in an action-packed 7-3 win over Sevilla on Wednesday.
Barcelona's injury crisis deepened on Wednesday after tests confirmed first-choice centre back Javier Mascherano will be out of action for upto 15 days after damaging a thigh muscle in Tuesday's 4-1 La Liga win at home to Real Sociedad.
Having absorbed the body blow of losing striker Radamel Falcao in the close season, Atletico Madrid have emerged as genuine contenders to break the title stranglehold of Real Madrid and Barcelona.
Eden Hazard finally scored his first goal for Real Madrid as his side beat second-placed Granada 4-2 in a highly entertaining game at the Santiago Bernabeu on Saturday to go four points clear at the top of La Liga.
Late Griezmann strike ends Atletico's away day hoodoo
Spanish soccer clubs Villarreal and Getafe have denied any wrongdoing after national media reported on Friday that police are investigating possible match-fixing in a 2-2 draw between the two clubs in La Liga last year. Newspaper El Pais reported that the match was being looked at as part of Operation Oikos, which was launched last year and led to 11 people being arrested on suspicion of forming a match-fixing group to profit from betting on games.
Barcelona closed to within four points of Real Madrid at the top of the La Liga after the leaders lost 3-2 at home to Valencia.
Real Madrid hit four goals in a devastating first-half spell as they beat Valencia 5-1 in the La Liga.
A total of 18 people, including three soccer players, are to stand trial for match-fixing, a judge in Pamplona ruled on Thursday.
A last-gasp strike from Ronaldo helped his side snatch a 3-2 win at Valladolid.
Real Betis right-back Emerson Aparecido's first year in La Liga went superbly well, but there is plenty to come from one of the league's most talented and determined rising stars.
La Liga leaders Barcelona hit two goals in the final three minutes to earn a 3-2 win at Rayo Vallecano
Images from football matches played across Europe on Sunday.
Real Madrid's unbeaten start to the La Liga season came to an abrupt and surprising end as Real Mallorca claimed a stunning 1-0 victory at a rocking Son Moix on Saturday to climb out of the relegation zone.
Barcelona have been frighteningly good at home this season, scoring 15 goals in three games at the Nou Camp.
Lionel Messi overhauled Real Madrid great Alfredo Di Stefano's La Liga goals tally as Barcelona and Atletico Madrid each won on Saturday to pull three points clear of Real at the top.
Champions Barcelona lost 2-0 at Celta Vigo while Getafe earned an important 2-0 win over Girona in their bid to secure Champions League qualification.
Real Madrid extended their lead in Spain to eight points after crushing Valladolid 7-0.
Barcelona suffered in the absence of the injured Lionel Messi as they drew 1-1 at home
Atletico coach Simeone defends VAR for making football fairer
Ousmane Dembele's late strike rescued a 1-1 draw for champions Barcelona at Atletico Madrid but Sevilla moved top with a 1-0 win over Real Valladolid. European champions Real Madrid were humiliated in a 3-0 defeat at Eibar.
Brazil midfielder Casemiro stretched Real's advantage right before halftime with a gut-busting run to meet a cross from compatriot Vinicius, but Levante hit back shortly after the interval through former Madrid forward Borja Mayoral.
Following September's 1-0 win over Espanyol, Real had five games without a win -- a run in which they went eight hours and one minute without scoring.
The Italian coach considers that having healthy players, such as striker Karim Benzema, will be the key to face the schedule that awaits the Madrid side, who will be looking to defend their LaLiga, Spanish Super Cup and Champions League titles.
Struggling Rayo win at Valladolid after late penalty save
With the Catalans shorn of three of their top forwards, all eyes will be on Griezmann in his first appearance at the Camp Nou since his 120-million-euro ($133 million) move from Atletico Madrid, and not least because Barca need a win to kickstart their season.
Barcelona's eight-game winning run was halted following a 2-2 draw with Valencia, Atletico Madrid lost 1-0 at Real Betis and a resurgent Real Madrid secured their fourth win in a row by beating Alaves 3-0.
Leaders Barcelona and Real Madrid were held to draws while Sevilla made up ground on the top two and Alaves slipped after a promising start. Here are five talking points from the weekend's La Liga action.
Real Madrid wasted a chance to keep the pressure on the top two in La Liga with a 2-2 draw away to Osasuna where Sergio Ramos was sent off and record signing Gareth Bale substituted.
Images from football matches played in La Liga and Serie A in Spain and Italy on Wednesday.
Images from the La Liga match played between FC Barcelona and Sevilla on at Camp Nou on Sunday
Athletic Bilbao ended Getafe's run of four straight wins and climbed above them into fifth place in La Liga when Aymeric Laporte's early bullet header secured a 1-0 win at the Coliseum in Madrid on Monday.
Atletico Madrid have been unable to repeat the magnificent achievements of last season in this campaign but can congratulate themselves on a job well done if they secure a lucrative Champions League berth on Saturday.
A summary of Saturday's action in Serie A and La Liga.
The Greek league leaders confirmed the move but did not give financial details. Local media said Toure would be paid around 2.5 million euros ($2.9 million) for one season.
Barcelona beat Girona 2-0 in a Catalan derby on Sunday to maintain their five-point lead at the top of La Liga, while Real Madrid thrashed Espanyol 4-2.